Our adipose tissue management system for use in reconstruction and cosmetic procedures.

About Breast Cancer

and breast reconstruction.

Breast cancer is the second most common cancer worldwide and each year around 1.7m women receive a new diagnosis of breast cancer1.

Annually in the UK around 55,000 women are diagnosed with breast cancer2.

Tissue & Cell Technologies estimates that 35,000 women p.a. in the UK undergo mastectomy (surgical removal of one or both breasts) or high-volume lumpectomy (breast conserving surgery – surgical removal of a discrete portion or lump of breast)*.

Of these, we estimate that around 25,000 women, in consultation with their treating clinician, may be eligible to consider lipomodelling – which is reconstruction of the breast using one’s own adipose tissue (i.e. fat) from a suitable part of the body.

The Opportunities

to improve existing methods.

Whilst lipomodelling is often considered to be the best approach for post-breast cancer reconstruction for many women, existing methods have the considerable drawbacks of requiring numerous adipose tissue harvest (liposuction) procedures under general anaesthetic; requiring overnight hospital stays for the patient; and, are very costly for healthcare providers (including NHS hospitals).

Specifically, the clinical issues with existing methods are:

A new solution was desperately needed to improve outcomes and meet the needs of hospitals, clinicians and patients: a better approach was to reduce the number of harvest procedures and this led to the development of the Adiposet™ system.

(The Adiposet™ system is) a significant advance in large volume fat transfer. It is cost effective, time saving and preferred by patients. The patients very much preferred the simple re-injection of stored fat under local anaesthetic or as a general anaesthetic day case because they have less pain and require no time off work.

Dr Eva Weiler-Mithoff | Consultant Plastic and Reconstructive Surgeon, Glasgow Royal Infirmary, UK

Our solution is Adiposet™

Tissue & Cell Technologies’ unique adipose tissue management system.

The key steps are:

  1. After harvesting, the patient’s adipose tissue is transported in a temperature controlled Adiposet™ tissue transport kit to Tissue & Cell Technologies’ dedicated facilities;
  2. Using strict protocols Tissue & Cell Technologies analyses the tissue to detect infections and processes it to remove unwanted material;
  3. The tissue is then frozen using a validated temperature controlled process and stored in a dedicated cryopreservation vessel at under -160°C;
  4. When the clinician requests more adipose tissue for re-injection, Tissue & Cell Technologies carefully thaws the required amount of tissue and prepares it in its controlled cleanrooms for grafting; and,
  5. The tissue is transported in an Adiposet™ transport kit back to the hospital for the re-injection procedure.

Click on the video below to see a short animation on how Adiposet works:

In summary, the needs and Adiposet’s solutions are:

Learn more about Adiposet™ benefits for::


*Of the 55,000 women diagnosed, 42% (23,200) had a mastectomy – i.e. the surgical removal of one or both breasts, partially or completely – as their primary therapeutic procedure3. In 2011 approximately 31% of these women (7,200) chose to have either immediate or delayed breast reconstruction4, which is around double the rate in the five years since 2006. Furthermore, in 2008 in the UK approximately 58% of women diagnosed with breast cancer underwent lumpectomy (breast conserving surgery – surgical removal of a discrete portion or lump of breast)5. Based on this data, the company estimates that approx. 35,000 women p.a. in the UK undergo mastectomy or high-volume lumpectomy.


  1. Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2015;136:E359-86
  2. Cancer Research UK, accessed September 2017
  3. NHS Choices, accessed September 2017
  4. [PDF] Jeevan R, Cromwell D, Browne J, et al. National Mastectomy and Breast Reconstruction Audit 2011. The NHS Information Centre 2011.
  5. Jeevan R, Browne J, van der Meulen J, Pereira J, Caddy C, Sheppard C, et al. First annual report of the National Mastectomy and Breast Reconstruction Audit 2008. NHS Information Centre, 2008